Mammalian fertilization
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منابع مشابه
Mammalian fertilization
fine,” says Waters. “But bustards have to be bill-fed.” After a period of quarantine in a special enclosure, they will eventually be released. The enclosure is open-topped to allow them to fly out to colonise surrounding fields. The immigrants have been taught to avoid both man and predators such as foxes using aversion therapy. Volunteers walk through the pen with dogs on leads, and if the bir...
متن کاملThe Molecules of Mammalian Fertilization
in some, ZP3 homologs are implicated as the key adhesion molecules, whereas in others, ZP2 homologs may play a dominant role (Topfer-Petersen et al., 1993). Although O-linked oligosaccharides on ZP3 are Dallas, Texas 75235 † Department of Cell Biology strongly implicated as being responsible for both sperm binding and signaling for the acrosome reaction, the University of Virginia Health Scienc...
متن کاملPervasive adaptive evolution in mammalian fertilization proteins.
Mammalian fertilization exhibits species specificity, and the proteins mediating sperm-egg interactions evolve rapidly between species. In this study, we demonstrate that the evolution of seven genes involved in mammalian fertilization is promoted by positive Darwinian selection by using likelihood ratio tests (LRTs). Several of these proteins are sperm proteins that have been implicated in bin...
متن کاملUnraveling the intricacies of mammalian fertilization
It is imperative to understand the molecular basis of various steps involved during fertilization. In the manuscript by Bianchi et al. a novel protein, Juno on egg membrane (oolemma) has been characterized that binds to sperm specific protein, Izumo-1. Monoclonal antibodies against Juno inhibited in vitro fertilization. Juno knock-out female mice failed to deliver litters on mating. It is rapid...
متن کاملIs Sperm Hyaluronidase Indispensable in Mammalian Fertilization?
Fertilization involves several precisely coordinated steps, including sperm dispersal of the oocyte cumulus mass, adhesion and binding to the zona pellucida, penetration through the zona pellucida, and fusion with the oocyte. Hyaluronidase, which is present in the sperm head, is known to be essential for the decomposition of the oocyte cumulus mass. Interestingly, two types of hyaluronidase—SPA...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2004
ISSN: 0960-9822
DOI: 10.1016/j.cub.2004.08.037